Telomeres Promise Biological Anti-Aging Potential of Human Life

Abstract

The telomeric shortening is linked to aging process. Telomerase reverses biological aging. Human body after the age of 35 years starts shrinking with reduction in number of cells. The body fights against aging, the harder it fights, the more tired it gets. The telomere is a biological clock, ticking down as we age and eventually leads to cell mortality. The life expectancy, life-span, and longevity are interrelated terms. They are basically anti-mortality and anti-aging. The maintenance of the genomic stability, DNA integrity and regulation of anti-aging cell physiology are biological foundation of immortality and anti-aging potential. The telomeric length (TL) is maintained by dynamic equilibrium between processes that lengthen and those that shorten telomeres. The cellular senescence perturbs this balance, fastens the aging and directs the mortality. The telomerase boosters and longevity enhancers natural products extend life-span and reduce the rate of biological aging. Their anti-mortality potentials and possible reasons of biological immortality which are beyond Hayflick limitation would be examined.